Khanna is a common last name in India. It can mean:
- Vikas Khanna, Michelin Star Chef, Author, Filmmaker, Host of MasterChef India and Twist of Taste
- Khanna, Ludhiana, a city in the Ludhiana district of Punjab
- Khanna (name), a prominent clan from the Dhai Ghar (Khatri) community of Punjab region
- Derek Khanna, political commentator and columnist