Ganesh Kumar Mani, is an Indian cardiothoracic and vascular surgeon, reported to have performed over 18000 Coronary artery bypass surgeries. He was honoured by the Government of India, in 2013, by bestowing on him the Padma Shri, the fourth highest civilian award, for his contributions to the fields of medicine and medical education. He was born on Delhi, India. did schooling at MEAHS School in the city to pass the higher secondary examination in 1964. Choosing medicine as his career, Mani graduated from the Maulana Azad Medical College, MBBS, in 1969 and secured the post graduate degree of MS in general surgery from the same institution in 1975. Subsequently, he joined the Christian Medical College and Hospital, Vellore, passed MCh in cardiothoracic surgery in 1979 and the next year, in 1980, passed MNAMS in cardiothoracic and vascular surgery from the National Academy of Medical Sciences.   

Dr. Mani started his career as a faculty member at the Christian Medical College and Hospital, Vellore and moved as the Specialist Surgeon to the Indian Railways Southern Railway HQ Hospital in Perambur in the south Indian state of Tamil Nadu, in 1984. He worked there till 1989 when he returned to Delhi as the Chief Cardiac Surgeon and Director of Cardiac Surgery at the Batra Hospital and Medical Research Centre, a position he held till 1995. The next move was as the Senior Cardiothoracic Consultant of the Apollo Hospital, Indraprastha, a 700 bedded tertiary care hospital in the Indian capital, working there from 1996 to 2003. He has also worked as the visiting consultant at hospitals such as Saroj Hospital, Delhi (2001-2003), Gandhi Medical College, Bhopal (2003), Delhi Heart and Lung Institute (2003-2009), Golden Heart Institute of the Jaipur Golden Hospital (2005-2009), the Mool Chand Hospital, Delhi (2008-2009) and as the Director of the Pushpanjali Institute of Cardiac Sciences and Crosslay Remedies.